There are 103 health care providers, specializing in Diagnostic Radiology, Interventional Pain Management, General Surgery, Interventional Radiology, Nuclear Medicine, Interventional Radiology, Nuclear Medicine, Pain Management, Interventional Pain Management, Interventional Radiology, Pain Management, Peripheral Vascular Disease, Interventional Pain Management, Peripheral Vascular Disease and more, being reported as members of the medical group. Renaissance Imaging Medical Associates Inc is a Medical Group that has 53 practice medical offices located in 12 states 36 cities in the USA. Miecznikowski, PhD, associate professor of biostatistics in the School of Public Health and Health Professions, is another co-author.Detailed information about Renaissance Imaging Medical Associates Inc in Los Angeles California. Rabi Yacoub, MD, assistant professor of medicine in the Division of Nephrology, is also a co-author. Worral, PhD, microscopy and histology core labs director Tomaszewski, MD, SUNY Distinguished Professor and the Peter A. Imtiaz Mohammad, PhD, lead histotechnologist in the histology core lab.
This project was supported by several grants from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health, including a Kidney Precision Medicine Project grant and a grant from the Human BioMolecular Atlas Program. Different types of staining can be used to highlight the podocytes, but sometimes the staining causes other important image information to be lost.
“It’s very challenging to identify podocytes in an image,” Govind says, noting there are so many cells in the glomerulus that it’s hard even for trained pathologists to figure out which nuclei belong to podocytes. The additional challenge with podocytes is that they are found deep within the glomeruli, the sac-like bundles of capillaries that handle first-line filtration of blood in the kidneys. One of the biggest challenges in dealing with images of biopsied tissue is that they contain huge amounts of data. “If one day we can track the loss of podocytes, then we can determine the stage of the disease.” Right now, that’s not possible, but it’s one of the goals of the UB research. “A healthy person has more podocytes than a sick person,” Sarder says. In the early stages of kidney disease, podocytes begin to change shape and, as the disease progresses, the number of them will fall.
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